The Sequoia Fund (SEQUX) is one of the most storied and reputable stock picking mutual funds. The fund and its manager (Ruane, Cunniff & Goldfarb) had a sterling reputation until the recent Valeant Pharmaceuticals debacle.
You can find the full transcript of the 2017 investor day here:
The fund's current top holdings (BRKA, MA, GOOGL, TJX, XRAY, KMX, CSU, RRC/LN):
On the firm's strategy to seek high quality companies:
On portfolio holding O'Reilly and competition by Amazon in the auto parts market:
On portfolio holding Credit Acceptance Corp and the subprime auto loan market: